Published: February 22, 2017 Abstract: Plants of the Cannabis genus are the only prolific producers of phytocannabinoids, compounds that strongly interact with the evolutionarily ancient endocannabinoid receptors shared by most bilaterian taxa. For millennia, the...
Research
terpenes
Why do plants produce so many terpenoid compounds?
Published: September 8, 2016 Abstract: All plants synthesize a suite of several hundred terpenoid compounds with roles that include phytohormones, protein modification reagents, anti-oxidants, and more. Different plant lineages also synthesize hundreds of distinct...
Multidimensional analysis of cannabis volatile constituents: Identification of 5,5-dimethyl-1- vinylbicyclo[2.1.1]hexane as a volatile marker of Hashish, the resin of Cannabis sativa L.
Published: November 2014 Abstract: The volatile constituents of drug samples derived from Cannabis sativa L. were investigated by means of headspace solid phase microextraction (HS-SPME) and gas chromatography techniques (GC-MS, GC × GC-MS). Samples of cannabis herb...
Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus
Published: September 5, 2018 Abstract: Cannabaceae plants Cannabis sativa L. and Humulus lupulus L. are rich in terpenes – both are typically comprised of terpenes as up to 3–5% of the dry-mass of the female inflorescence. Terpenes of cannabis and hops are typically...
Extraction and Analysis of Terpenes/Terpenoids
Published: June 10, 2016 Abstract: Terpenes/terpenoids constitute one of the largest classes of natural products, this is due to the incredible chemical diversity that can arise from the biochemical transformations of the relatively simple prenyl diphosphate starter...
Processing and extraction methods of medicinal cannabis: a narrative review
Published: July 19, 2021 Abstract: Introduction: As the cannabis industry transitions from a black market to a legal market, product development, and methods of extraction have become a focal point. To date, more than thousands of chemical constituents have been...
The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders
Published: February, 2020 Abstract: Mood disorders are the most prevalent mental conditions encountered in psychiatric practice. Numerous patients suffering from mood disorders present with treatment-resistant forms of depression, co-morbid anxiety, other psychiatric...
Non-Cannabinoid Metabolites of Cannabis sativa L. with Therapeutic Potential
Published: February 20, 2021 Abstract: The cannabis plant (Cannabis sativa L.) produces an estimated 545 chemical compounds of different biogenetic classes. In addition to economic value, many of these phytochemicals have medicinal and physiological activity. The...
The anti-inflammatory and analgesic effects of formulated full-spectrum cannabis extract in the treatment of neuropathic pain associated with multiple sclerosis
Published: April 1, 2020 Abstract: Purpose: Cannabis has been used for thousands of years in many cultures for the treatment of several ailments including pain. The benefits of cannabis are mediated largely by cannabinoids, the most prominent of which are...
Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science
Published: August 27, 2018 Abstract: Background: Comprehensive literature reviews of historical perspectives and evidence supporting cannabis/cannabinoids in the treatment of pain, including migraine and headache, with associated neurobiological mechanisms of pain...